Entity Details

Primary name PTN23_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H3S7
EntryNamePTN23_HUMAN
FullNameTyrosine-protein phosphatase non-receptor type 23
TaxID9606
Evidenceevidence at protein level
Length1636
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesPTPN23

GO terms

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GOName
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0010633 negative regulation of epithelial cell migration
GO:0015031 protein transport
GO:0016604 nuclear body
GO:0019901 protein kinase binding
GO:0032456 endocytic recycling
GO:0036064 ciliary basal body
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0045022 early endosome to late endosome transport
GO:0060271 cilium assembly
GO:0061357 positive regulation of Wnt protein secretion
GO:0070062 extracellular exosome
GO:0071345 cellular response to cytokine stimulus
GO:1903387 positive regulation of homophilic cell adhesion
GO:1903393 positive regulation of adherens junction organization
GO:2000643 positive regulation of early endosome to late endosome transport

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Early endosome
Endosome
Nucleus

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR004328 BRO1 domainDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR025304 ALIX V-shaped domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR038499 BRO1 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
PTN23_HUMANDDX24_HUMANHPRD, IntAct16169070 details
PTN23_HUMANGRB2_HUMANBioGRID, IntAct, UniProt20936779 21179510 26344197 28514442 28675297 details
PTN23_HUMANGRAP2_HUMANBioGRID, IntAct, UniProt21179510 26186194 28514442 details
PTN23_HUMANTS101_HUMANBioGRID, MINT17174262 26456826 details
PTN23_HUMANCHM4B_HUMANBioGRID, DIP, MINT17174262 18434552 26866605 details
PTN23_HUMANPDCD6_HUMANMINT17174262 details
PTN23_HUMANSH3G2_HUMANBioGRID, MINT17174262 details
PTN23_HUMANFAK1_HUMANMINT18835089 details
PTN23_HUMANCEP55_HUMANBioGRID, IntAct25416956 details
PTN23_HUMANTRI27_HUMANBioGRID, IntAct25416956 details
PTN23_HUMANNT2NA_HUMANBioGRID, IntAct25416956 31515488 details
PTN23_HUMANPSA3_HUMANBioGRID, IntAct25416956 details
PTN23_HUMANCEP19_HUMANBioGRID, IntAct32296183 details
PTN23_HUMANALG2_HUMANBioGRID17174262 details
PTN23_HUMANLRRK2_HUMANBioGRID19001729 details
PTN23_HUMANSTAM2_HUMANBioGRID23477725 26866605 details
PTN23_HUMANNT2NC_HUMANBioGRID25416956 details
PTN23_HUMANUBAP1_HUMANBioGRID21757351 26456826 27839950 details
PTN23_HUMANUBC_HUMANBioGRID26456826 details
PTN23_HUMANSRC_HUMANMINT18835089 details
PTN23_HUMANPDC6I_HUMANBioGRID17174262 details
PTN23_HUMANITA4_HUMANBioGRID22623428 details
PTN23_HUMANEGFR_HUMANBioGRID23477725 details
PTN23_HUMANHGS_HUMANBioGRID23477725 26456826 details
PTN23_HUMANUBP8_HUMANBioGRID23477725 details
PTN23_HUMANSTAM1_HUMANBioGRID26456826 details
PTN23_HUMANSMAP2_HUMANBioGRID29395067 details