Entity Details

Primary name GPAT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HCL2
EntryNameGPAT1_HUMAN
FullNameGlycerol-3-phosphate acyltransferase 1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length828
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesGPAM

GO terms

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GOName
GO:0001817 regulation of cytokine production
GO:0004366 glycerol-3-phosphate O-acyltransferase activity
GO:0005741 mitochondrial outer membrane
GO:0005886 plasma membrane
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006631 fatty acid metabolic process
GO:0006637 acyl-CoA metabolic process
GO:0006651 diacylglycerol biosynthetic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0006655 phosphatidylglycerol biosynthetic process
GO:0008654 phospholipid biosynthetic process
GO:0009749 response to glucose
GO:0016021 integral component of membrane
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0019432 triglyceride biosynthetic process
GO:0031966 mitochondrial membrane
GO:0033146 regulation of intracellular estrogen receptor signaling pathway
GO:0040018 positive regulation of multicellular organism growth
GO:0042104 positive regulation of activated T cell proliferation
GO:0051607 defense response to virus
GO:0055089 fatty acid homeostasis
GO:0055091 phospholipid homeostasis
GO:0070236 negative regulation of activation-induced cell death of T cells
GO:0102420 sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR002123 Phospholipid/glycerol acyltransferaseDomainDomain
IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferaseFamilyFamily
IPR028354 Glycerol-3-phosphate acyltransferase, PlsBFamilyFamily
IPR041728 GPAT/DHAPAT, acyltransferase domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
GPAT1_HUMANCIDEB_HUMANBioGRID, IntAct32296183 details
GPAT1_HUMANA4_HUMANBioGRID21244100 21832049 details
GPAT1_HUMANFBX7_HUMANBioGRID27503909 details