Entity Details

Primary name DDX4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQI0
EntryNameDDX4_HUMAN
FullNameProbable ATP-dependent RNA helicase DDX4
TaxID9606
Evidenceevidence at protein level
Length724
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesDDX4

GO terms

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GOName
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007140 male meiotic nuclear division
GO:0007141 male meiosis I
GO:0007275 multicellular organism development
GO:0007276 gamete generation
GO:0007283 spermatogenesis
GO:0010529 negative regulation of transposition
GO:0016887 ATP hydrolysis activity
GO:0030154 cell differentiation
GO:0030317 flagellated sperm motility
GO:0031047 gene silencing by RNA
GO:0034587 piRNA metabolic process
GO:0043046 DNA methylation involved in gamete generation
GO:0043186 P granule
GO:0048471 perinuclear region of cytoplasm
GO:0071546 pi-body
GO:0071547 piP-body
GO:1990511 piRNA biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000629 ATP-dependent RNA helicase DEAD-box, conserved siteSiteConserved site
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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