Entity Details

Primary name BFAR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZS9
EntryNameBFAR_HUMAN
FullNameBifunctional apoptosis regulator
TaxID9606
Evidenceevidence at protein level
Length450
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesBFAR

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0005783 endoplasmic reticulum
GO:0005887 integral component of plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptotic process
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030674 protein-macromolecule adaptor activity
GO:0043066 negative regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046872 metal ion binding
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0089720 caspase binding
GO:1903895 negative regulation of IRE1-mediated unfolded protein response

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001660 Sterile alpha motif domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site

Diseases

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