Entity Details

Primary name TRI33_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UPN9
EntryNameTRI33_HUMAN
FullNameE3 ubiquitin-protein ligase TRIM33
TaxID9606
Evidenceevidence at protein level
Length1127
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesTRIM33

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0008270 zinc ion binding
GO:0016567 protein ubiquitination
GO:0016740 transferase activity
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001487 BromodomainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003649 B-box, C-terminalDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR027370 RING-type zinc-finger, LisH dimerisation motifDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
TRI33_HUMANSMAD4_HUMANBioGRID, IntAct, MINT19135894 20603019 21597466 21726812 23788427 24307592 24382352 28115363 details
TRI33_HUMANSMAD3_HUMANBioGRID, MINT16751102 18003620 19917253 21597466 22196728 24382352 details
TRI33_HUMANTIF1A_HUMANBioGRID, DIP, HPRD, IntAct, MINT12096914 21531907 24820418 24981860 26496610 30479348 31753913 details
TRI33_HUMANNLGN3_HUMANBioGRID, IntAct25464930 details
TRI33_HUMANTRI33_HUMANBioGRID12096914 20603019 details
TRI33_HUMANH31_HUMANBioGRID22196728 details
TRI33_HUMANUB2D3_HUMANBioGRID21726812 25172487 details
TRI33_HUMANDHX33_HUMANBioGRID25172487 details
TRI33_HUMANUBE2N_HUMANBioGRID25172487 details
TRI33_HUMANUB2E1_HUMANBioGRID25172487 details
TRI33_HUMANCTNB1_HUMANBioGRID25639486 details
TRI33_HUMANERG_HUMANBioGRID27626314 details
TRI33_HUMANUB2D2_HUMANBioGRID29643511 details
TRI33_HUMANSMAD2_HUMANBioGRID, IntAct16751102 18003620 19135894 20603019 22196728 23788427 details
TRI33_HUMANSKIL_HUMANBioGRID, IntAct20603019 25059663 31753913 details
TRI33_HUMANLDB1_HUMANBioGRID, IntAct20447379 20603019 details
TRI33_HUMANCDC16_HUMANBioGRID, IntAct23160376 28514442 31753913 details
TRI33_HUMANTIF1B_HUMANBioGRID, DIP21531907 28068325 29955894 details
TRI33_HUMANNCOR1_HUMANBioGRID14527417 details
TRI33_HUMANTFE2_HUMANBioGRID20603019 details
TRI33_HUMANAPC1_HUMANBioGRID23160376 31753913 details
TRI33_HUMANCDC27_HUMANBioGRID23160376 details
TRI33_HUMANAPC4_HUMANBioGRID23160376 details
TRI33_HUMANAPC5_HUMANBioGRID23160376 details
TRI33_HUMANAPC7_HUMANBioGRID23160376 details
TRI33_HUMANCDC23_HUMANBioGRID23160376 31753913 details
TRI33_HUMANCDC20_HUMANBioGRID23160376 details
TRI33_HUMANBUB1B_HUMANBioGRID23160376 details
TRI33_HUMANCCNA2_HUMANBioGRID23160376 details
TRI33_HUMANUBC9_HUMANBioGRID23788427 25059663 details
TRI33_HUMANCRYAB_HUMANBioGRID24307592 details
TRI33_HUMANSEM1_HUMANBioGRID24515614 details
TRI33_HUMANSEML_HUMANBioGRID24515614 details
TRI33_HUMANZBTB1_HUMANBioGRID24657165 details
TRI33_HUMANCHD1L_HUMANBioGRID23926104 details
TRI33_HUMANFZR1_HUMANBioGRID23160376 details
TRI33_HUMANTHOC1_HUMANBioGRID29395067 details