Entity Details

Primary name MAN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2U8
EntryNameMAN1_HUMAN
FullNameInner nuclear membrane protein Man1
TaxID9606
Evidenceevidence at protein level
Length911
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesLEMD3

GO terms

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GOName
GO:0005637 nuclear inner membrane
GO:0005639 integral component of nuclear inner membrane
GO:0006998 nuclear envelope organization
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0031490 chromatin DNA binding
GO:0031965 nuclear membrane
GO:0032926 negative regulation of activin receptor signaling pathway
GO:1902531 regulation of intracellular signal transduction

Subcellular Location

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Subcellular Location
Nucleus inner membrane

Domains

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DomainNameCategoryType
IPR003887 LEM domainDomainDomain
IPR011015 LEM/LEM-like domain superfamilyFamilyHomologous superfamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR018996 Man1/Src1, C-terminalDomainDomain
IPR034394 MAN1, RNA recognition motifDomainDomain
IPR034997 Inner nuclear membrane protein Man1FamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR041885 MAN1, winged-helix domainFamilyHomologous superfamily

Diseases

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