Entity Details

Primary name RAMP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60895
EntryNameRAMP2_HUMAN
FullNameReceptor activity-modifying protein 2
TaxID9606
Evidenceevidence at protein level
Length175
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesRAMP2

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001605 adrenomedullin receptor activity
GO:0001666 response to hypoxia
GO:0002040 sprouting angiogenesis
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005905 clathrin-coated pit
GO:0006816 calcium ion transport
GO:0006886 intracellular protein transport
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007507 heart development
GO:0007565 female pregnancy
GO:0008217 regulation of blood pressure
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0015026 coreceptor activity
GO:0015031 protein transport
GO:0031623 receptor internalization
GO:0032092 positive regulation of protein binding
GO:0032355 response to estradiol
GO:0032570 response to progesterone
GO:0032870 cellular response to hormone stimulus
GO:0034333 adherens junction assembly
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0043116 negative regulation of vascular permeability
GO:0043235 receptor complex
GO:0045766 positive regulation of angiogenesis
GO:0070830 bicellular tight junction assembly
GO:0070831 basement membrane assembly
GO:0072659 protein localization to plasma membrane
GO:0097084 vascular associated smooth muscle cell development
GO:0097647 amylin receptor signaling pathway
GO:0150057 amylin receptor complex 2
GO:1903143 adrenomedullin receptor complex
GO:1990409 adrenomedullin binding
GO:1990410 adrenomedullin receptor signaling pathway
GO:2000352 negative regulation of endothelial cell apoptotic process
GO:2001214 positive regulation of vasculogenesis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR006985 Receptor activity modifying proteinFamilyFamily
IPR038126 RAMP domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01278 PramlintideDrugbanksmall molecule