Entity Details

Primary name AT2C2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75185
EntryNameAT2C2_HUMAN
FullNameCalcium-transporting ATPase type 2C member 2
TaxID9606
Evidenceevidence at protein level
Length946
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesATP2C2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005384 manganese ion transmembrane transporter activity
GO:0005388 P-type calcium transporter activity
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006828 manganese ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0008553 P-type proton-exporting transporter activity
GO:0009898 cytoplasmic side of plasma membrane
GO:0015410 ABC-type manganese transporter activity
GO:0016021 integral component of membrane
GO:0016887 ATP hydrolysis activity
GO:0031410 cytoplasmic vesicle
GO:0032588 trans-Golgi network membrane
GO:0034220 ion transmembrane transport
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0061180 mammary gland epithelium development
GO:0070588 calcium ion transmembrane transport
GO:0072659 protein localization to plasma membrane
GO:0090280 positive regulation of calcium ion import

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR006413 P-type ATPase, subfamily IIA, PMR1-typeFamilyFamily
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR030334 Calcium-transporting ATPase type 2C member 2FamilyFamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01189 DesfluraneDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AT2C2_HUMANCRCM1_HUMANIntAct20887894 details