Entity Details

Primary name NDUS3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75489
EntryNameNDUS3_HUMAN
FullNameNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length264
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesNDUFS3

GO terms

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GOName
GO:0003954 NADH dehydrogenase activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0005759 mitochondrial matrix
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0009055 electron transfer activity
GO:0016604 nuclear body
GO:0021762 substantia nigra development
GO:0030308 negative regulation of cell growth
GO:0031966 mitochondrial membrane
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0072593 reactive oxygen species metabolic process
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunitDomainDomain
IPR010218 NADH dehydrogenase, subunit CFamilyFamily
IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved siteSiteConserved site
IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00997 DoxorubicinDrugbanksmall molecule