Entity Details

Primary name PKHG5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94827
EntryNamePKHG5_HUMAN
FullNamePleckstrin homology domain-containing family G member 5
TaxID9606
Evidenceevidence at protein level
Length1006
SequenceStatuscomplete
DateCreated2007-10-23
DateModified2021-06-02

Ontological Relatives

GenesPLEKHG5

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007266 Rho protein signal transduction
GO:0030027 lamellipodium
GO:0030139 endocytic vesicle
GO:0030424 axon
GO:0035767 endothelial cell chemotaxis
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043542 endothelial cell migration
GO:0048471 perinuclear region of cytoplasm
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR040181 Pleckstrin homology domain-containing family G member 5/7FamilyFamily

Diseases

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