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Entity Details
Primary name
REC8_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O95072
EntryName
REC8_HUMAN
FullName
Meiotic recombination protein REC8 homolog
TaxID
9606
Evidence
evidence at protein level
Length
547
SequenceStatus
complete
DateCreated
2004-01-16
DateModified
2021-06-02
Ontological Relatives
Genes
REC8
GO terms
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GO
Name
GO:0000795
synaptonemal complex
GO:0000800
lateral element
GO:0001556
oocyte maturation
GO:0001673
male germ cell nucleus
GO:0003682
chromatin binding
GO:0005634
nucleus
GO:0007062
sister chromatid cohesion
GO:0007064
mitotic sister chromatid cohesion
GO:0007130
synaptonemal complex assembly
GO:0007131
reciprocal meiotic recombination
GO:0007141
male meiosis I
GO:0007283
spermatogenesis
GO:0007286
spermatid development
GO:0009566
fertilization
GO:0034990
nuclear mitotic cohesin complex
GO:0034991
nuclear meiotic cohesin complex
GO:0051177
meiotic sister chromatid cohesion
GO:0051321
meiotic cell cycle
GO:0072520
seminiferous tubule development
GO:1990414
replication-born double-strand break repair via sister chromatid exchange
Subcellular Location
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Subcellular Location
Chromosome
Nucleus
Domains
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Domain
Name
Category
Type
IPR006909
Rad21/Rec8-like protein, C-terminal, eukaryotic
Domain
Domain
IPR006910
Rad21/Rec8-like protein, N-terminal
Domain
Domain
IPR036390
Winged helix DNA-binding domain superfamily
Family
Homologous superfamily
IPR039781
Rad21/Rec8-like protein
Family
Family
Diseases
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Drugs
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Interactions
13 interactions
Interactor
Partner
Sources
Publications
Link
REC8_HUMAN
MLF1_HUMAN
IntAct
25036637
details
REC8_HUMAN
MLF2_HUMAN
IntAct
25036637
details
REC8_HUMAN
BAG2_HUMAN
BioGRID, IntAct, MINT
24981860
25036637
details
REC8_HUMAN
PSMD2_HUMAN
IntAct
25036637
details
REC8_HUMAN
SGTA_HUMAN
IntAct
25036637
details
REC8_HUMAN
STIP1_HUMAN
IntAct
25036637
details
REC8_HUMAN
CHIP_HUMAN
BioGRID, IntAct, MINT
24981860
25036637
details
REC8_HUMAN
CYBP_HUMAN
IntAct
25036637
details
REC8_HUMAN
PTG3L_HUMAN
IntAct
25036637
details
REC8_HUMAN
AASD1_HUMAN
IntAct
25036637
details
REC8_HUMAN
SMC3_HUMAN
BioGRID, MINT
12759374
24981860
details
REC8_HUMAN
SYCP3_HUMAN
BioGRID
12759374
details
REC8_HUMAN
SMC1B_HUMAN
BioGRID
12759374
details
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