Entity Details

Primary name CCN4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95388
EntryNameCCN4_HUMAN
FullNameCCN family member 4
TaxID9606
Evidenceevidence at protein level
Length367
SequenceStatuscomplete
DateCreated2003-08-15
DateModified2021-06-02

Ontological Relatives

GenesCCN4

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001817 regulation of cytokine production
GO:0005178 integrin binding
GO:0005520 insulin-like growth factor binding
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008201 heparin binding
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016055 Wnt signaling pathway
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030316 osteoclast differentiation
GO:0031012 extracellular matrix
GO:0032331 negative regulation of chondrocyte differentiation
GO:0042593 glucose homeostasis
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050729 positive regulation of inflammatory response
GO:0060348 bone development
GO:0060548 negative regulation of cell death
GO:0090303 positive regulation of wound healing

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000867 Insulin-like growth factor-binding protein, IGFBPDomainDomain
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001007 VWFC domainDomainDomain
IPR006207 Cystine knot, C-terminalDomainDomain
IPR006208 Glycoprotein hormone subunit betaDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR012395 IGFBP-related, CNNFamilyFamily
IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved siteSiteConserved site
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR043973 CCN, TSP1 domainDomainDomain

Diseases

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Interactions

5 interactions