Entity Details

Primary name SVIL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95425
EntryNameSVIL_HUMAN
FullNameSupervillin
TaxID9606
Evidenceevidence at protein level
Length2214
SequenceStatuscomplete
DateCreated2005-01-04
DateModified2021-06-02

Ontological Relatives

GenesSVIL

GO terms

Show/Hide Table
GOName
GO:0002102 podosome
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007519 skeletal muscle tissue development
GO:0008154 actin polymerization or depolymerization
GO:0015629 actin cytoskeleton
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0032467 positive regulation of cytokinesis
GO:0036449 microtubule minus-end
GO:0042995 cell projection
GO:0043034 costamere
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cell projection
Cleavage furrow
Cytoplasm
Midbody

Domains

Show/Hide Table
DomainNameCategoryType
IPR003128 Villin headpieceDomainDomain
IPR007122 Villin/GelsolinFamilyFamily
IPR007123 Gelsolin-like domainDomainDomain
IPR015628 SupervillinFamilyFamily
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily
IPR036886 Villin headpiece domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

81 interactions

InteractorPartnerSourcesPublicationsLink
SVIL_HUMANLC7L2_HUMANBioGRID, HPRD, IntAct16169070 details
SVIL_HUMANNEBU_HUMANHPRD, MINT18639526 details
SVIL_HUMANZNF16_HUMANUniProt21874239 details
SVIL_HUMANMYPC3_HUMANIntAct21569246 details
SVIL_HUMANFLNA_HUMANBioGRID, HPRD, IntAct20309963 26496610 details
SVIL_HUMANLIMA1_HUMANBioGRID, HPRD, IntAct20309963 26496610 details
SVIL_HUMANPCNA_HUMANUniProt26030842 details
SVIL_HUMANANDR_HUMANBioGRID, HPRD11792840 details
SVIL_HUMANESR1_HUMANBioGRID11792840 details
SVIL_HUMANPPARG_HUMANBioGRID11792840 details
SVIL_HUMANGCR_HUMANBioGRID11792840 details
SVIL_HUMANK1C18_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANMI4GD_HUMANBioGRID, HPRD16880273 20309963 details
SVIL_HUMANUXT_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANCENPR_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANBUB1_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANCENPF_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANHAX1_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANHS90A_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANKIFC3_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANLMNA_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANLMNB2_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANMPP9_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANNDKB_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANODFP2_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANPAN3_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANPCX3_HUMANBioGRID20309963 details
SVIL_HUMANHMMR_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANBACD2_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANATRX_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANKIF14_HUMANBioGRID, HPRD20309963 31586073 details
SVIL_HUMANMRTFB_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANKMT2A_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANSPD2A_HUMANBioGRID, HPRD19109420 20309963 details
SVIL_HUMANKIF22_HUMANBioGRID, HPRD20309963 details
SVIL_HUMANSTAR9_HUMANBioGRID20309963 details
SVIL_HUMANTRIP6_HUMANBioGRID, HPRD16880273 details
SVIL_HUMANDYLT1_HUMANBioGRID, HPRD16880273 details
SVIL_HUMANUBP7_HUMANBioGRID23382381 details
SVIL_HUMANMYH9_HUMANBioGRID, HPRD, IntAct12202484 17925381 26496610 details
SVIL_HUMANH4_HUMANBioGRID, IntAct30021884 details
SVIL_HUMANSPTB2_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANSPTN1_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANMYH2_HUMANBioGRID12202484 details
SVIL_HUMANCLH1_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANMYO1G_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANACTN4_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANACTN1_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANVIME_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANLYN_HUMANBioGRID12202484 details
SVIL_HUMANFLOT1_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANFLOT2_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANACTB_HUMANBioGRID, HPRD12202484 34079125 details
SVIL_HUMANGNAI1_HUMANBioGRID12202484 details
SVIL_HUMANGBB1_HUMANBioGRID12202484 details
SVIL_HUMANSTOM_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANGPSM3_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANML12B_HUMANBioGRID12202484 details
SVIL_HUMANML12A_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANCALM1_HUMANBioGRID12202484 details
SVIL_HUMANCALM2_HUMANBioGRID12202484 details
SVIL_HUMANCALM3_HUMANBioGRID12202484 details
SVIL_HUMANGAPR1_HUMANBioGRID, HPRD12202484 details
SVIL_HUMANTGFI1_HUMANHPRD11792840 details
SVIL_HUMANP2RX7_HUMANHPRD11707406 details
SVIL_HUMAN1433G_HUMANHPRD15324660 details
SVIL_HUMANSRC8_HUMANHPRD19109420 details
SVIL_HUMANMYH10_HUMANHPRD17925381 details
SVIL_HUMANMYLK_HUMANHPRD17925381 details
SVIL_HUMANGOGA2_HUMANHPRD16880273 details
SVIL_HUMANAMOL2_HUMANHPRD16880273 details
SVIL_HUMANLPP_HUMANHPRD16880273 details
SVIL_HUMANCTBP2_HUMANHPRD16880273 details
SVIL_HUMANMD1L1_HUMANHPRD16880273 details
SVIL_HUMANBIP_HUMANHPRD16880273 details
SVIL_HUMANKIF4A_HUMANHPRD16880273 details
SVIL_HUMANGNAI2_HUMANHPRD12202484 details
SVIL_HUMANMMP25_HUMANHPRD12202484 details
SVIL_HUMANGBB2_HUMANHPRD12202484 details
SVIL_HUMANCAMP_HUMANHPRD12202484 details
SVIL_HUMANCAV3_HUMANHPRD12711699 details