Entity Details

Primary name ERR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95718
EntryNameERR2_HUMAN
FullNameSteroid hormone receptor ERR2
TaxID9606
Evidenceevidence at protein level
Length433
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesESRRB

GO terms

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GOName
GO:0000785 chromatin
GO:0000793 condensed chromosome
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0000993 RNA polymerase II complex binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005496 steroid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008283 cell population proliferation
GO:0017145 stem cell division
GO:0019827 stem cell population maintenance
GO:0043565 sequence-specific DNA binding
GO:0043697 cell dedifferentiation
GO:0045494 photoreceptor cell maintenance
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0045821 positive regulation of glycolytic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048839 inner ear development
GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle
GO:1902459 positive regulation of stem cell population maintenance
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000035 regulation of stem cell division
GO:2000737 negative regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR024178 Estrogen receptor/oestrogen-related receptorFamilyFamily
IPR027289 Oestrogen-related receptorFamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00255 DiethylstilbestrolDrugbanksmall molecule
DB01645 GenisteinDrugbanksmall molecule
DB07776 FlavoneDrugbanksmall molecule