Entity Details

Primary name IGHG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01857
EntryNameIGHG1_HUMAN
FullNameImmunoglobulin heavy constant gamma 1
TaxID9606
Evidenceevidence at protein level
Length330
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003823 antigen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0008228 opsonization
GO:0009897 external side of plasma membrane
GO:0018149 peptide cross-linking
GO:0019221 cytokine-mediated signaling pathway
GO:0030449 regulation of complement activation
GO:0034987 immunoglobulin receptor binding
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042571 immunoglobulin complex, circulating
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0050853 B cell receptor signaling pathway
GO:0050871 positive regulation of B cell activation
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01631 Methyl nonanoateDrugbanksmall molecule
DB03740 N-acetyl-alpha-D-glucosamineDrugbanksmall molecule
DB04473 alpha-L-fucoseDrugbanksmall molecule
DB04639 BiphenylalanineDrugbanksmall molecule
DB07371 3-(10-methyl-9-anthryl)propanoic acidDrugbanksmall molecule
DB07375 EtiocholanedioneDrugbanksmall molecule
DB07441 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACIDDrugbanksmall molecule
DB07672 TRANS-2-(DIMETHYLPHENYLSILYL)-PIPERIDINE-N-OXIDEDrugbanksmall molecule
DB07764 FluorescinDrugbanksmall molecule
DB07816 N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACIDDrugbanksmall molecule
DB07881 N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINEDrugbanksmall molecule
DB07883 (2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONEDrugbanksmall molecule
DB07909 (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOLDrugbanksmall molecule
DB08294 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACIDDrugbanksmall molecule
DB08296 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACIDDrugbanksmall molecule
DB08332 9-(2-carboxyethyl)-10-methylanthracene endoperoxideDrugbanksmall molecule
DB08377 N-[4-(4-nitrophenylphospho)butanoyl]-D-alanineDrugbanksmall molecule
DB08394 PARA-NITROPHENYLPHOSPHONOBUTANOYL-GLYCINEDrugbanksmall molecule
DB08409 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINEDrugbanksmall molecule
DB08410 PARA-NITROBENZYL GLUTARYL GLYCINIC ACIDDrugbanksmall molecule
DB08411 N-[4-(4-nitrophenylphospho)butanoyl]-L-alanineDrugbanksmall molecule
DB08412 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACIDDrugbanksmall molecule
DB08562 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACIDDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB15258 ImlifidaseDrugbankbiotech