Entity Details

Primary name RET4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02753
EntryNameRET4_HUMAN
FullNameRetinol-binding protein 4
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesRBP4

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0001654 eye development
GO:0002639 positive regulation of immunoglobulin production
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006094 gluconeogenesis
GO:0007507 heart development
GO:0007601 visual perception
GO:0016918 retinal binding
GO:0019841 retinol binding
GO:0030277 maintenance of gastrointestinal epithelium
GO:0030324 lung development
GO:0032024 positive regulation of insulin secretion
GO:0032526 response to retinoic acid
GO:0032991 protein-containing complex
GO:0034632 retinol transmembrane transporter activity
GO:0034633 retinol transport
GO:0042572 retinol metabolic process
GO:0042593 glucose homeostasis
GO:0044877 protein-containing complex binding
GO:0045471 response to ethanol
GO:0048562 embryonic organ morphogenesis
GO:0048706 embryonic skeletal system development
GO:0048738 cardiac muscle tissue development
GO:0048807 female genitalia morphogenesis
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0060065 uterus development
GO:0060068 vagina development
GO:0060157 urinary bladder development
GO:0060347 heart trabecula formation
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000566 Lipocalin/cytosolic fatty-acid binding domainDomainDomain
IPR002449 Retinol binding protein/PurpurinFamilyFamily
IPR012674 CalycinFamilyHomologous superfamily
IPR022271 Lipocalin, ApoD typeFamilyFamily
IPR022272 Lipocalin family conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00162 Vitamin ADrugbanksmall molecule
DB00755 TretinoinDrugbanksmall molecule
DB03917 N-EthylretinamideSwissprotsmall molecule
DB05076 FenretinideSwissprotsmall molecule
DB06755 Beta caroteneSwissprotsmall molecule
DB06985 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acidSwissprotsmall molecule