Entity Details

Primary name NU1M_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP03886
EntryNameNU1M_HUMAN
FullNameNADH-ubiquinone oxidoreductase chain 1
TaxID9606
Evidenceevidence at protein level
Length318
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesND1

GO terms

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GOName
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0009060 aerobic respiration
GO:0014070 response to organic cyclic compound
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0031966 mitochondrial membrane
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0033194 response to hydroperoxide
GO:0042493 response to drug
GO:0043025 neuronal cell body

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit HFamilyFamily
IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00753 IsofluraneDrugbanksmall molecule
DB01028 MethoxyfluraneDrugbanksmall molecule
DB01159 HalothaneDrugbanksmall molecule
DB01189 DesfluraneDrugbanksmall molecule
DB01236 SevofluraneDrugbanksmall molecule
DB04464 N-FormylmethionineDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule