Entity Details

Primary name GSTM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09488
EntryNameGSTM1_HUMAN
FullNameGlutathione S-transferase Mu 1
TaxID9606
Evidenceevidence at protein level
Length218
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesGSTM1

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006693 prostaglandin metabolic process
GO:0006749 glutathione metabolic process
GO:0018916 nitrobenzene metabolic process
GO:0019899 enzyme binding
GO:0042178 xenobiotic catabolic process
GO:0042803 protein homodimerization activity
GO:0043295 glutathione binding
GO:0045171 intercellular bridge
GO:0051122 hepoxilin biosynthetic process
GO:0070458 cellular detoxification of nitrogen compound
GO:1901687 glutathione derivative biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003081 Glutathione S-transferase, Mu classFamilyFamily
IPR004045 Glutathione S-transferase, N-terminalDomainDomain
IPR004046 Glutathione S-transferase, C-terminalDomainDomain
IPR010987 Glutathione S-transferase, C-terminal-likeDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR036282 Glutathione S-transferase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR040079 Glutathione Transferase familyFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB00316 AcetaminophenDrugbanksmall molecule
DB00515 CisplatinDrugbanksmall molecule
DB00526 OxaliplatinSwissprotsmall molecule
DB00608 ChloroquineDrugbanksmall molecule
DB00958 CarboplatinSwissprotsmall molecule
DB00993 AzathioprineDrugbanksmall molecule
DB01008 BusulfanSwissprotsmall molecule
DB01020 Isosorbide mononitrateDrugbanksmall molecule
DB01834 (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthreneDrugbanksmall molecule
DB02165 Zinc trihydroxideDrugbanksmall molecule
DB02458 S-(2,4-dinitrophenyl)glutathioneDrugbanksmall molecule
DB03310 Glutathione disulfideDrugbanksmall molecule
DB03314 5-fluorotryptophanDrugbanksmall molecule
DB04187 (9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthreneDrugbanksmall molecule
DB11672 CurcuminDrugbanksmall molecule

Interactions

4 interactions