Entity Details

Primary name MBL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11226
EntryNameMBL2_HUMAN
FullNameMannose-binding protein C
TaxID9606
Evidenceevidence at protein level
Length248
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMBL2

GO terms

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GOName
GO:0001867 complement activation, lectin pathway
GO:0005102 signaling receptor binding
GO:0005537 mannose binding
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0006953 acute-phase response
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0006979 response to oxidative stress
GO:0008228 opsonization
GO:0009986 cell surface
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0048306 calcium-dependent protein binding
GO:0048525 negative regulation of viral process
GO:0050830 defense response to Gram-positive bacterium
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR033990 Collectin, C-type lectin-like domainDomainDomain
IPR037570 Mannose-binding protein CFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01818 O3-SulfonylgalactoseDrugbanksmall molecule
DB01979 Methyl alpha-D-mannosideDrugbanksmall molecule
DB02837 4-(Hydrogen sulfate)-beta-D-galactopyranoseDrugbanksmall molecule
DB03194 Methyl beta-L-fucopyranosideDrugbanksmall molecule
DB03721 N-acetyl-alpha-neuraminic acidDrugbanksmall molecule
DB03879 alpha-L-methyl-fucoseDrugbanksmall molecule
DB04426 Alpha-Methyl-N-Acetyl-D-GlucosamineDrugbanksmall molecule