Entity Details

Primary name OXDA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14920
EntryNameOXDA_HUMAN
FullNameD-amino-acid oxidase
TaxID9606
Evidenceevidence at protein level
Length347
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesDAO

GO terms

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GOName
GO:0003884 D-amino-acid oxidase activity
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006562 proline catabolic process
GO:0008104 protein localization
GO:0019478 D-amino acid catabolic process
GO:0019752 carboxylic acid metabolic process
GO:0036088 D-serine catabolic process
GO:0042416 dopamine biosynthetic process
GO:0042802 identical protein binding
GO:0055130 D-alanine catabolic process
GO:0070178 D-serine metabolic process
GO:0071949 FAD binding

Subcellular Location

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Subcellular Location
Peroxisome

Domains

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DomainNameCategoryType
IPR006076 FAD dependent oxidoreductaseDomainDomain
IPR006181 D-amino acid oxidase, conserved siteSiteConserved site
IPR023209 D-amino-acid oxidaseFamilyFamily

Diseases

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Disease IDSourceNameDescription
181500 OMIMSchizophrenia (SCZD)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Drugs

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DrugNameSourceType
DB02838 3,4-Dihydro-2h-Pyrrolium-5-CarboxylateDrugbanksmall molecule
DB02988 Imino-TryptophanDrugbanksmall molecule
DB03147 Flavin adenine dinucleotideDrugbanksmall molecule
DB03225 D-TryptophanDrugbanksmall molecule
DB03531 Flavin-adenine dinucleotide-N5-isobutyl ketoneDrugbanksmall molecule
DB03793 Benzoic acidDrugbanksmall molecule
DB04166 Anthranilic acidDrugbanksmall molecule
DB07979 (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACIDDrugbanksmall molecule