Entity Details

Primary name CR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17927
EntryNameCR1_HUMAN
FullNameComplement receptor type 1
TaxID9606
Evidenceevidence at protein level
Length2039
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesCR1

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0001851 complement component C3b binding
GO:0001855 complement component C4b binding
GO:0001861 complement component C4b receptor activity
GO:0001970 positive regulation of activation of membrane attack complex
GO:0001971 negative regulation of activation of membrane attack complex
GO:0002430 complement receptor mediated signaling pathway
GO:0002435 immune complex clearance by erythrocytes
GO:0002638 negative regulation of immunoglobulin production
GO:0004877 complement component C3b receptor activity
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0007009 plasma membrane organization
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0030449 regulation of complement activation
GO:0030667 secretory granule membrane
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0042130 negative regulation of T cell proliferation
GO:0043312 neutrophil degranulation
GO:0044853 plasma membrane raft
GO:0045589 regulation of regulatory T cell differentiation
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0045916 negative regulation of complement activation
GO:0045918 negative regulation of cytolysis
GO:0045957 negative regulation of complement activation, alternative pathway
GO:0045959 negative regulation of complement activation, classical pathway
GO:0070062 extracellular exosome
GO:0101003 ficolin-1-rich granule membrane
GO:1900004 negative regulation of serine-type endopeptidase activity
GO:1900005 positive regulation of serine-type endopeptidase activity
GO:1900099 negative regulation of plasma cell differentiation
GO:1904669 ATP export

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily

Diseases

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