Entity Details

Primary name ITB6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18564
EntryNameITB6_HUMAN
FullNameIntegrin beta-6
TaxID9606
Evidenceevidence at protein level
Length788
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesITGB6

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001618 virus receptor activity
GO:0005178 integrin binding
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008305 integrin complex
GO:0009615 response to virus
GO:0009897 external side of plasma membrane
GO:0016477 cell migration
GO:0030054 cell junction
GO:0030198 extracellular matrix organization
GO:0033627 cell adhesion mediated by integrin
GO:0034685 integrin alphav-beta6 complex
GO:0038023 signaling receptor activity
GO:0042060 wound healing
GO:0043129 surfactant homeostasis
GO:0043235 receptor complex
GO:0043588 skin development
GO:0048286 lung alveolus development
GO:0055091 phospholipid homeostasis
GO:0060022 hard palate development
GO:0060348 bone development
GO:0060395 SMAD protein signal transduction
GO:0060435 bronchiole development
GO:0061520 Langerhans cell differentiation
GO:0070166 enamel mineralization
GO:0071479 cellular response to ionizing radiation
GO:0071604 transforming growth factor beta production
GO:1901388 regulation of transforming growth factor beta activation

Subcellular Location

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Subcellular Location
Cell junction
Membrane

Domains

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DomainNameCategoryType
IPR002369 Integrin beta subunit, VWA domainDomainDomain
IPR012896 Integrin beta subunit, tailDomainDomain
IPR013111 EGF-like domain, extracellularDomainDomain
IPR014836 Integrin beta subunit, cytoplasmic domainDomainDomain
IPR015436 Integrin beta-6 subunitFamilyFamily
IPR015812 Integrin beta subunitFamilyFamily
IPR016201 PSI domainDomainDomain
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily
IPR033760 Integrin beta N-terminalDomainDomain
IPR036349 Integrin beta tail domain superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR040622 Integrin beta, epidermal growth factor-like domain 1DomainDomain

Diseases

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