Entity Details

Primary name FSHR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23945
EntryNameFSHR_HUMAN
FullNameFollicle-stimulating hormone receptor
TaxID9606
Evidenceevidence at protein level
Length695
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesFSHR

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004963 follicle-stimulating hormone receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007283 spermatogenesis
GO:0007292 female gamete generation
GO:0008406 gonad development
GO:0008528 G protein-coupled peptide receptor activity
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0009755 hormone-mediated signaling pathway
GO:0010738 regulation of protein kinase A signaling
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0042699 follicle-stimulating hormone signaling pathway
GO:0043235 receptor complex
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071372 cellular response to follicle-stimulating hormone stimulus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR002131 Glycoprotein hormone receptor familyFamilyFamily
IPR002272 Follicle stimulating hormone receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR024635 Gonadotropin hormone receptor, transmembrane domainDomainDomain
IPR026906 BspA type Leucine rich repeat regionRepeatRepeat

Diseases

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Drugs

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DrugNameSourceType
DB00032 MenotropinsDrugbankbiotech
DB00066 FollitropinDrugbankbiotech
DB00094 UrofollitropinDrugbankbiotech
DB00097 Choriogonadotropin alfaDrugbankbiotech
DB04786 SuraminDrugbanksmall molecule
DB09066 Corifollitropin alfaDrugbankbiotech