Entity Details

Primary name LAMA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP25391
EntryNameLAMA1_HUMAN
FullNameLaminin subunit alpha-1
TaxID9606
Evidenceevidence at protein level
Length3075
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesLAMA1

GO terms

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GOName
GO:0002011 morphogenesis of an epithelial sheet
GO:0005102 signaling receptor binding
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005606 laminin-1 complex
GO:0005608 laminin-3 complex
GO:0005615 extracellular space
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007411 axon guidance
GO:0008022 protein C-terminus binding
GO:0009887 animal organ morphogenesis
GO:0009888 tissue development
GO:0016020 membrane
GO:0030155 regulation of cell adhesion
GO:0030198 extracellular matrix organization
GO:0030334 regulation of cell migration
GO:0031012 extracellular matrix
GO:0043010 camera-type eye development
GO:0043208 glycosphingolipid binding
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0045995 regulation of embryonic development
GO:0048514 blood vessel morphogenesis
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060445 branching involved in salivary gland morphogenesis
GO:0061304 retinal blood vessel morphogenesis
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000034 Laminin IVDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR008211 Laminin, N-terminalDomainDomain
IPR009254 Laminin alpha, domain IDomainDomain
IPR010307 Laminin domain IIDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB06245 LanoteplaseDrugbankbiotech