Entity Details

Primary name DPOD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28340
EntryNameDPOD1_HUMAN
FullNameDNA polymerase delta catalytic subunit
TaxID9606
Evidenceevidence at protein level
Length1107
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesPOLD1

GO terms

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GOName
GO:0000109 nucleotide-excision repair complex
GO:0000166 nucleotide binding
GO:0000723 telomere maintenance
GO:0000731 DNA synthesis involved in DNA repair
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006298 mismatch repair
GO:0008296 3'-5'-exodeoxyribonuclease activity
GO:0009411 response to UV
GO:0016020 membrane
GO:0016235 aggresome
GO:0019985 translesion synthesis
GO:0032201 telomere maintenance via semi-conservative replication
GO:0033683 nucleotide-excision repair, DNA incision
GO:0034644 cellular response to UV
GO:0042769 DNA damage response, detection of DNA damage
GO:0043625 delta DNA polymerase complex
GO:0045004 DNA replication proofreading
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0055089 fatty acid homeostasis
GO:0070987 error-free translesion synthesis
GO:0071897 DNA biosynthetic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006133 DNA-directed DNA polymerase, family B, exonuclease domainDomainDomain
IPR006134 DNA-directed DNA polymerase, family B, multifunctional domainDomainDomain
IPR006172 DNA-directed DNA polymerase, family BFamilyFamily
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR017964 DNA-directed DNA polymerase, family B, conserved siteSiteConserved site
IPR023211 DNA polymerase, palm domain superfamilyFamilyHomologous superfamily
IPR025687 C4-type zinc-finger of DNA polymerase deltaDomainDomain
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily
IPR042087 DNA polymerase family B, thumb domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
DPOD1_HUMANSCG1_HUMANBioGRID, HPRD, IntAct16169070 details
DPOD1_HUMANCE126_HUMANBioGRID, HPRD, IntAct16169070 details
DPOD1_HUMANDPOD2_HUMANBioGRID, HPRD, IntAct, MINT, UniProt12403614 16510448 26344197 26496610 27684187 28514442 31449058 9286699 details
DPOD1_HUMANDPOD4_HUMANBioGRID, IntAct, MINT, UniProt12403614 16510448 26496610 31449058 details
DPOD1_HUMANPCNA_HUMANBioGRID, HPRD, IntAct, UniProt11328591 12171929 12403614 14988403 15805117 16510448 20227374 24768535 24958773 26496610 details
DPOD1_HUMANABL1_HUMANIntAct17474147 details
DPOD1_HUMANSRC_HUMANIntAct17474147 details
DPOD1_HUMANFYN_HUMANIntAct17474147 details
DPOD1_HUMANGRB2_HUMANIntAct17474147 details
DPOD1_HUMANTE2IP_HUMANbhf-ucl, BioGRID21044950 34079125 details
DPOD1_HUMANKLH12_HUMANIntAct32296183 details
DPOD1_HUMANCRTP1_HUMANIntAct32296183 details
DPOD1_HUMANATL4_HUMANBioGRID, IntAct32296183 details
DPOD1_HUMANLASP1_HUMANBioGRID, IntAct32296183 details
DPOD1_HUMANATR_HUMANBioGRID10608806 details
DPOD1_HUMANSLD5_HUMANBioGRID21705323 details
DPOD1_HUMANCDK4_HUMANBioGRID9545286 details
DPOD1_HUMANCCND3_HUMANBioGRID9545286 details
DPOD1_HUMANCDK2_HUMANBioGRID, HPRD9545286 details
DPOD1_HUMANCCNE1_HUMANBioGRID9545286 details
DPOD1_HUMANMCPH1_HUMANBioGRID29150431 details
DPOD1_HUMANRB_HUMANBioGRID11114723 details
DPOD1_HUMANYPEL3_HUMANBioGRID32296183 details
DPOD1_HUMANTRI55_HUMANBioGRID31391242 details
DPOD1_HUMANSUMO2_HUMANBioGRID32786267 details
DPOD1_HUMANDPOD3_HUMANBioGRID, HPRD, IntAct, MINT, UniProt10852724 11328591 12403614 16510448 26496610 27684187 31449058 details
DPOD1_HUMANGBRL2_HUMANIntAct17353931 details
DPOD1_HUMANARF6_HUMANIntAct17353931 details
DPOD1_HUMANMAGA6_HUMANIntAct17353931 details
DPOD1_HUMANGSTK1_HUMANIntAct17353931 details
DPOD1_HUMANWRIP1_HUMANBioGRID, HPRD, UniProt15670210 details
DPOD1_HUMANDDX20_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANE2AK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANRBM14_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANEAF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANNAF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANNOLC1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANMFAP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANATRX_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANAP3B1_HUMANBioGRID, IntAct27173435 unassigned1312 details
DPOD1_HUMANMMS19_HUMANBioGRID, IntAct22678361 22678362 28178521 details
DPOD1_HUMANCIA2B_HUMANBioGRID, IntAct23891004 28178521 details
DPOD1_HUMANCND3_HUMANBioGRID16543152 details
DPOD1_HUMANRENT1_HUMANBioGRID16488880 details
DPOD1_HUMANRENT2_HUMANBioGRID16488880 details
DPOD1_HUMANMGMT_HUMANBioGRID16226712 details
DPOD1_HUMANTERF2_HUMANBioGRID20811636 details
DPOD1_HUMANERPG3_HUMANBioGRID20541997 details
DPOD1_HUMANERCC6_HUMANBioGRID20541997 details
DPOD1_HUMANXRCC1_HUMANBioGRID20227374 details
DPOD1_HUMANPOLK_HUMANBioGRID20227374 details
DPOD1_HUMANDHX9_HUMANBioGRID15995249 details
DPOD1_HUMANSPRTN_HUMANBioGRID23254330 27871366 details
DPOD1_HUMANRN126_HUMANBioGRID26508657 details
DPOD1_HUMANRAD51_HUMANBioGRID28757209 details
DPOD1_HUMANUBR5_HUMANBioGRID31586398 details
DPOD1_HUMANHAUS7_HUMANHPRD12806015 details
DPOD1_HUMANXRCC5_HUMANHPRD12393188 details