Entity Details

Primary name SPB3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29508
EntryNameSPB3_HUMAN
FullNameSerpin B3
TaxID9606
Evidenceevidence at protein level
Length390
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesSERPINB3

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0002020 protease binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008284 positive regulation of cell population proliferation
GO:0010466 negative regulation of peptidase activity
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010950 positive regulation of endopeptidase activity
GO:0010951 negative regulation of endopeptidase activity
GO:0030335 positive regulation of cell migration
GO:0031410 cytoplasmic vesicle
GO:0031982 vesicle
GO:0035425 autocrine signaling
GO:0035578 azurophil granule lumen
GO:0038001 paracrine signaling
GO:0043086 negative regulation of catalytic activity
GO:0043312 neutrophil degranulation
GO:0043508 negative regulation of JUN kinase activity
GO:0045861 negative regulation of proteolysis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03929 D-SerineDrugbanksmall molecule
DB04522 DexfosfoserineDrugbanksmall molecule