Entity Details

Primary name GDIA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31150
EntryNameGDIA_HUMAN
FullNameRab GDP dissociation inhibitor alpha
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesGDI1

GO terms

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GOName
GO:0005092 GDP-dissociation inhibitor activity
GO:0005093 Rab GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0030424 axon
GO:0030496 midbody
GO:0031267 small GTPase binding
GO:0032482 Rab protein signal transduction
GO:0032991 protein-containing complex
GO:0043025 neuronal cell body
GO:0043209 myelin sheath
GO:0043547 positive regulation of GTPase activity
GO:0045773 positive regulation of axon extension
GO:0050771 negative regulation of axonogenesis
GO:0051592 response to calcium ion
GO:0090315 negative regulation of protein targeting to membrane

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000806 Rab GDI proteinFamilyFamily
IPR018203 GDP dissociation inhibitorFamilyFamily
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
GDIA_HUMANUBQL4_HUMANBioGRID, HPRD, IntAct16713569 details
GDIA_HUMANGNL1_HUMANBioGRID, IntAct18255255 details
GDIA_HUMANKITH_HUMANBioGRID, MINT21900206 details
GDIA_HUMANRAB4A_HUMANBioGRID, IntAct, UniProt19570034 26496610 28514442 34079125 details
GDIA_HUMANLNX1_HUMANBioGRID, IntAct25416956 25910212 details
GDIA_HUMANRAB9A_HUMANBioGRID, HPRD, IntAct26496610 28514442 34079125 7744738 details
GDIA_HUMANRAB3B_HUMANBioGRID11741295 details
GDIA_HUMANCDC42_HUMANBioGRID, HPRD11583574 details
GDIA_HUMANOGT1_HUMANBioGRID32994395 details
GDIA_HUMANEPB41_HUMANHPRD16368544 details
GDIA_HUMANFBX11_HUMANIntAct17353931 details
GDIA_HUMANTRM7_HUMANIntAct17353931 details
GDIA_HUMANHLAB_HUMANIntAct17353931 details
GDIA_HUMAN1433Z_HUMANMINT15161933 details
GDIA_HUMANRAB1A_HUMANBioGRID, IntAct, MINT19942850 22939629 26344197 26496610 28514442 details
GDIA_HUMANRAB7A_HUMANBioGRID, IntAct26496610 28514442 29360040 details
GDIA_HUMANRAB6A_HUMANBioGRID, HPRD, IntAct26496610 28514442 8175798 details
GDIA_HUMANSOAT1_HUMANBioGRID, IntAct27173435 unassigned1312 details
GDIA_HUMANNDUS1_HUMANBioGRID, IntAct27173435 unassigned1312 details
GDIA_HUMANACAP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
GDIA_HUMANRAB1B_HUMANBioGRID, HPRD, IntAct26186194 28514442 8836150 details
GDIA_HUMANDISC1_HUMANIntAct31413325 details
GDIA_HUMANMIC10_HUMANBioGRID22114354 details
GDIA_HUMANRHOH_HUMANHPRD11809807 details
GDIA_HUMANRAC2_HUMANHPRD9490022 details
GDIA_HUMANPRAF1_HUMANHPRD10751420 details
GDIA_HUMANRB27A_HUMANHPRD12802062 details
GDIA_HUMANPSN1_HUMANHPRD15480879 details