Entity Details

Primary name GASR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32239
EntryNameGASR_HUMAN
FullNameGastrin/cholecystokinin type B receptor
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesCCKBR

GO terms

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GOName
GO:0001696 gastric acid secretion
GO:0004951 cholecystokinin receptor activity
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008284 positive regulation of cell population proliferation
GO:0015054 gastrin receptor activity
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0031741 type B gastrin/cholecystokinin receptor binding
GO:0038188 cholecystokinin signaling pathway
GO:0045851 pH reduction
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity
GO:0048565 digestive tract development
GO:0048732 gland development

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000314 Gastrin receptorFamilyFamily
IPR009126 Cholecystokinin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00183 PentagastrinDrugbanksmall molecule
DB08862 CholecystokininDrugbanksmall molecule