Entity Details

Primary name CCR7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32248
EntryNameCCR7_HUMAN
FullNameC-C chemokine receptor type 7
TaxID9606
Evidenceevidence at protein level
Length378
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesCCR7

GO terms

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GOName
GO:0001768 establishment of T cell polarity
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002407 dendritic cell chemotaxis
GO:0002408 myeloid dendritic cell chemotaxis
GO:0002606 positive regulation of dendritic cell antigen processing and presentation
GO:0002885 positive regulation of hypersensitivity
GO:0002922 positive regulation of humoral immune response
GO:0004930 G protein-coupled receptor activity
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016493 C-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0030838 positive regulation of actin filament polymerization
GO:0031274 positive regulation of pseudopodium assembly
GO:0031529 ruffle organization
GO:0032496 response to lipopolysaccharide
GO:0032649 regulation of interferon-gamma production
GO:0032651 regulation of interleukin-1 beta production
GO:0032695 negative regulation of interleukin-12 production
GO:0032735 positive regulation of interleukin-12 production
GO:0034695 response to prostaglandin E
GO:0035757 chemokine (C-C motif) ligand 19 binding
GO:0035758 chemokine (C-C motif) ligand 21 binding
GO:0038117 C-C motif chemokine 19 receptor activity
GO:0038121 C-C motif chemokine 21 receptor activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045060 negative thymic T cell selection
GO:0045785 positive regulation of cell adhesion
GO:0045860 positive regulation of protein kinase activity
GO:0046330 positive regulation of JNK cascade
GO:0048872 homeostasis of number of cells
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051491 positive regulation of filopodium assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0060326 cell chemotaxis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071345 cellular response to cytokine stimulus
GO:0071731 response to nitric oxide
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090630 activation of GTPase activity
GO:0097022 lymphocyte migration into lymph node
GO:0097029 mature conventional dendritic cell differentiation
GO:2000147 positive regulation of cell motility
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000522 positive regulation of immunological synapse formation
GO:2000525 positive regulation of T cell costimulation
GO:2000526 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
GO:2000547 regulation of dendritic cell dendrite assembly
GO:2000669 negative regulation of dendritic cell apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR001718 CC chemokine receptor 7FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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