Entity Details

Primary name ABCD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP33897
EntryNameABCD1_HUMAN
FullNameATP-binding cassette sub-family D member 1
TaxID9606
Evidenceevidence at protein level
Length745
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesABCD1

GO terms

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GOName
GO:0002082 regulation of oxidative phosphorylation
GO:0005324 long-chain fatty acid transporter activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006635 fatty acid beta-oxidation
GO:0006869 lipid transport
GO:0007031 peroxisome organization
GO:0015607 ABC-type fatty-acyl-CoA transporter activity
GO:0015910 long-chain fatty acid import into peroxisome
GO:0015919 peroxisomal membrane transport
GO:0016020 membrane
GO:0016887 ATP hydrolysis activity
GO:0019899 enzyme binding
GO:0030497 fatty acid elongation
GO:0031966 mitochondrial membrane
GO:0031998 regulation of fatty acid beta-oxidation
GO:0032000 positive regulation of fatty acid beta-oxidation
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0036109 alpha-linolenic acid metabolic process
GO:0036113 very long-chain fatty-acyl-CoA catabolic process
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042758 long-chain fatty acid catabolic process
GO:0042760 very long-chain fatty acid catabolic process
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043217 myelin maintenance
GO:0043531 ADP binding
GO:0043651 linoleic acid metabolic process
GO:0045046 protein import into peroxisome membrane
GO:0048471 perinuclear region of cytoplasm
GO:0051900 regulation of mitochondrial depolarization
GO:0055089 fatty acid homeostasis
GO:0055092 sterol homeostasis
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1900407 regulation of cellular response to oxidative stress
GO:1903427 negative regulation of reactive oxygen species biosynthetic process
GO:1990535 neuron projection maintenance
GO:2001280 positive regulation of unsaturated fatty acid biosynthetic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Lysosome membrane
Mitochondrion membrane
Peroxisome membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR005283 Peroxysomal long chain fatty acyl transporterFamilyFamily
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031237 ATP-binding cassette sub-family D member 1FamilyFamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily

Diseases

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