Entity Details

Primary name CH3L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36222
EntryNameCH3L1_HUMAN
FullNameChitinase-3-like protein 1
TaxID9606
Evidenceevidence at protein level
Length383
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCHI3L1

GO terms

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GOName
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008061 chitin binding
GO:0009612 response to mechanical stimulus
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0030246 carbohydrate binding
GO:0030324 lung development
GO:0031012 extracellular matrix
GO:0032757 positive regulation of interleukin-8 production
GO:0034612 response to tumor necrosis factor
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0045766 positive regulation of angiogenesis
GO:0048471 perinuclear region of cytoplasm
GO:0051216 cartilage development
GO:0051897 positive regulation of protein kinase B signaling
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0070741 response to interleukin-6
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Secreted

Domains

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DomainNameCategoryType
IPR001223 Glycoside hydrolase family 18, catalytic domainDomainDomain
IPR011583 Chitinase IIDomainDomain
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR028538 Chitinase-3-like protein 1FamilyFamily
IPR029070 Chitinase insertion domain superfamilyFamilyHomologous superfamily

Diseases

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