Entity Details

Primary name RL5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP46777
EntryNameRL5_HUMAN
FullName60S ribosomal protein L5
TaxID9606
Evidenceevidence at protein level
Length297
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesRPL5

GO terms

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GOName
GO:0000027 ribosomal large subunit assembly
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0002181 cytoplasmic translation
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0003735 structural constituent of ribosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0006364 rRNA processing
GO:0006412 translation
GO:0006413 translational initiation
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0008097 5S rRNA binding
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0019083 viral transcription
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0042273 ribosomal large subunit biogenesis
GO:0045727 positive regulation of translation
GO:0048027 mRNA 5'-UTR binding
GO:0050821 protein stabilization
GO:0070062 extracellular exosome
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1904667 negative regulation of ubiquitin protein ligase activity
GO:1990904 ribonucleoprotein complex
GO:1990948 ubiquitin ligase inhibitor activity
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
GO:2000435 negative regulation of protein neddylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR005485 Ribosomal protein L5 eukaryotic/L18 archaealFamilyFamily
IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminalDomainDomain

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
RL5_HUMANCSK2B_HUMANBioGRID, HPRD, IntAct10094392 10491318 11710515 14667819 8806611 9042965 9738462 details
RL5_HUMANRENT2_HUMANBioGRID, HPRD, IntAct15231747 details
RL5_HUMANPDCD4_HUMANBioGRID, HPRD, IntAct12054647 details
RL5_HUMANMDM2_HUMANBioGRID, HPRD, I2D, IntAct, MINT14612427 15308643 15314173 15314174 17110929 17116689 17242401 17373842 18426907 18560357 20547751 20554519 21097889 21399665 21925390 23169665 26908445 29547122 29702115 30252118 30320499 32198344 32483207 32516735 7935455 8827714 details
RL5_HUMANDCC_HUMANBioGRID, IntAct20434207 details
RL5_HUMANSURF2_HUMANBioGRID, IntAct, MINT21900206 26186194 28514442 details
RL5_HUMANT22D1_HUMANBioGRID, MINT21900206 details
RL5_HUMANCSK21_HUMANBioGRID, HPRD, IntAct10491318 22113938 details
RL5_HUMANIF5A1_HUMANBioGRID, HPRD9465063 details
RL5_HUMANIPO13_HUMANBioGRID11447110 details
RL5_HUMANOSTP_HUMANBioGRID22779921 details
RL5_HUMANRL5_HUMANBioGRID, HPRD15231747 23169665 details
RL5_HUMANVHL_HUMANBioGRID22234250 details
RL5_HUMANCLK1_HUMANBioGRID26167880 details
RL5_HUMANP73_HUMANBioGRID25301064 details
RL5_HUMANSPIN1_HUMANBioGRID29547122 details
RL5_HUMANERPG3_HUMANBioGRID31722399 details
RL5_HUMANERCC6_HUMANBioGRID31722399 details
RL5_HUMANOGT1_HUMANBioGRID32994395 details
RL5_HUMANPPM1D_HUMANHPRD7649987 details
RL5_HUMANNVL_HUMANHPRD15469983 details
RL5_HUMANM3K14_HUMANHPRD, IntAct14743126 14743216 details
RL5_HUMAN1433Z_HUMANMINT15161933 details
RL5_HUMANRS23_HUMANBioGRID, IntAct20434207 22939629 26344197 details
RL5_HUMANP53_HUMANBioGRID, MINT15308643 22653443 23169665 23443559 30252118 32807901 details
RL5_HUMANNOP56_HUMANBioGRID, IntAct12777385 22939629 26496610 34079125 details
RL5_HUMANNPM_HUMANBioGRID, IntAct16648475 26186194 26496610 details
RL5_HUMANRL4_HUMANBioGRID, DIP22939629 25866880 26344197 26908445 details
RL5_HUMANRRP1B_HUMANBioGRID, IntAct19710015 20926688 details
RL5_HUMANRL23_HUMANBioGRID, IntAct15308643 17116689 22939629 26344197 30021884 details
RL5_HUMANAMFR_HUMANBioGRID17681147 details
RL5_HUMANRL11_HUMANBioGRID15308643 17116689 17242401 18560357 22939629 23169665 26344197 29547122 details
RL5_HUMANHDAC5_HUMANBioGRID21081666 details
RL5_HUMANMTOR_HUMANBioGRID21045808 details
RL5_HUMANH2B3B_HUMANBioGRID21846774 details
RL5_HUMANRL22_HUMANBioGRID22939629 26344197 29207594 details
RL5_HUMANHS90A_HUMANBioGRID16263121 22939629 details
RL5_HUMANPML_HUMANBioGRID23169665 details
RL5_HUMANATM_HUMANBioGRID30252118 details
RL5_HUMANMARCS_HUMANBioGRID30942445 details
RL5_HUMANIPO5_HUMANHPRD9687515 details
RL5_HUMANIMB1_HUMANHPRD9687515 details
RL5_HUMANTNPO1_HUMANHPRD9687515 details
RL5_HUMANTNIP1_HUMANHPRD9687515 details
RL5_HUMANIPO7_HUMANHPRD9687515 details
RL5_HUMANHARS1_HUMANHPRD8049265 details