Entity Details

Primary name VEGFB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49765
EntryNameVEGFB_HUMAN
FullNameVascular endothelial growth factor B
TaxID9606
Evidenceevidence at protein level
Length207
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesVEGFB

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002040 sprouting angiogenesis
GO:0002576 platelet degranulation
GO:0005172 vascular endothelial growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006493 protein O-linked glycosylation
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0010629 negative regulation of gene expression
GO:0016020 membrane
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031093 platelet alpha granule lumen
GO:0035470 positive regulation of vascular wound healing
GO:0038084 vascular endothelial growth factor signaling pathway
GO:0042056 chemoattractant activity
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043183 vascular endothelial growth factor receptor 1 binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0045766 positive regulation of angiogenesis
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050930 induction of positive chemotaxis
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0060048 cardiac muscle contraction
GO:0060754 positive regulation of mast cell chemotaxis
GO:0060976 coronary vasculature development
GO:0070374 positive regulation of ERK1 and ERK2 cascade

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000072 PDGF/VEGF domainDomainDomain
IPR023581 Platelet-derived growth factor, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08885 AfliberceptDrugbankbiotech