Entity Details

Primary name RB27A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51159
EntryNameRB27A_HUMAN
FullNameRas-related protein Rab-27A
TaxID9606
Evidenceevidence at protein level
Length221
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesRAB27A

GO terms

Show/Hide Table
GOName
GO:0001750 photoreceptor outer segment
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006605 protein targeting
GO:0006887 exocytosis
GO:0007596 blood coagulation
GO:0010628 positive regulation of gene expression
GO:0016324 apical plasma membrane
GO:0019003 GDP binding
GO:0019882 antigen processing and presentation
GO:0019904 protein domain specific binding
GO:0030141 secretory granule
GO:0030318 melanocyte differentiation
GO:0030425 dendrite
GO:0030667 secretory granule membrane
GO:0031489 myosin V binding
GO:0032400 melanosome localization
GO:0032402 melanosome transport
GO:0032585 multivesicular body membrane
GO:0033093 Weibel-Palade body
GO:0033162 melanosome membrane
GO:0035580 specific granule lumen
GO:0036257 multivesicular body organization
GO:0042470 melanosome
GO:0043312 neutrophil degranulation
GO:0043316 cytotoxic T cell degranulation
GO:0043320 natural killer cell degranulation
GO:0045921 positive regulation of exocytosis
GO:0048489 synaptic vesicle transport
GO:0050766 positive regulation of phagocytosis
GO:0070062 extracellular exosome
GO:0070382 exocytic vesicle
GO:0071985 multivesicular body sorting pathway
GO:0097278 complement-dependent cytotoxicity
GO:1903307 positive regulation of regulated secretory pathway
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1903435 positive regulation of constitutive secretory pathway
GO:1990182 exosomal secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Late endosome
Lysosome
Melanosome
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR041837 Rab27a/bFamilyFamily

Diseases

Show/Hide Table

Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
RB27A_HUMANERG28_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANCSN6_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANRBM48_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANGDF9_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANCE126_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANEF1A1_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANZBT16_HUMANBioGRID, HPRD, IntAct16169070 details
RB27A_HUMANMELPH_HUMANBioGRID, DIP, HPRD, IntAct, MINT, UniProt11773082 11856727 11980908 12062444 12446441 12897212 15059972 17045265 25312756 details
RB27A_HUMANSYTL1_HUMANBioGRID, HPRD, IntAct11773082 11980908 12590134 15998322 32296183 details
RB27A_HUMANSYTL4_HUMANBioGRID, HPRD, IntAct11773082 11865063 12101244 12176990 12590134 24700782 32296183 details
RB27A_HUMANSYTL5_HUMANBioGRID, HPRD, IntAct12051743 12590134 32296183 details
RB27A_HUMANMYRIP_HUMANBioGRID, HPRD, IntAct12590134 32296183 details
RB27A_HUMANSYTL3_HUMANBioGRID, HPRD, IntAct11773082 12590134 32296183 details
RB27A_HUMANUN13D_HUMANBioGRID, HPRD, IntAct14699162 16278825 25312756 details
RB27A_HUMANRPH3L_HUMANBioGRID, HPRD12578829 14593078 details
RB27A_HUMANSYTL2_HUMANBioGRID11773082 11980908 12590134 details
RB27A_HUMANLRIF1_HUMANBioGRID, HPRD16169070 details
RB27A_HUMANMYO5A_HUMANBioGRID, HPRD12006666 12062444 details
RB27A_HUMANA4_HUMANBioGRID21832049 details
RB27A_HUMANADRB2_HUMANBioGRID24561123 details
RB27A_HUMANRIF1_HUMANIntAct16169070 details
RB27A_HUMANRP3A_HUMANBioGRID, HPRD, IntAct12578829 28514442 details
RB27A_HUMANEXPH5_HUMANBioGRID11773082 details
RB27A_HUMANUN13B_HUMANBioGRID24043286 details
RB27A_HUMANSYT1_HUMANBioGRID22740627 details
RB27A_HUMANSTX1A_HUMANHPRD12101244 details
RB27A_HUMANGDIA_HUMANHPRD12802062 details
RB27A_HUMANRIMS1_HUMANHPRD12578829 details
RB27A_HUMANRIMS2_HUMANHPRD12578829 details
RB27A_HUMANGRAB_HUMANHPRD11266473 details
RB27A_HUMANPGTB2_HUMANHPRD12802062 details