Entity Details

Primary name DLX5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56178
EntryNameDLX5_HUMAN
FullNameHomeobox protein DLX-5
TaxID9606
Evidenceevidence at protein level
Length289
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDLX5

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0001958 endochondral ossification
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008283 cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0021889 olfactory bulb interneuron differentiation
GO:0030154 cell differentiation
GO:0030326 embryonic limb morphogenesis
GO:0030509 BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0042472 inner ear morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 roof of mouth development
GO:0060166 olfactory pit development
GO:0060325 face morphogenesis
GO:0071773 cellular response to BMP stimulus
GO:0071837 HMG box domain binding
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097376 interneuron axon guidance
GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain
IPR022135 Distal-less-like homeobox protein, N-terminal domainDomainDomain

Diseases

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