Entity Details

Primary name RELN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78509
EntryNameRELN_HUMAN
FullNameReelin
TaxID9606
Evidenceevidence at protein level
Length3460
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesRELN

GO terms

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GOName
GO:0000904 cell morphogenesis involved in differentiation
GO:0001764 neuron migration
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0008236 serine-type peptidase activity
GO:0010001 glial cell differentiation
GO:0010976 positive regulation of neuron projection development
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0021511 spinal cord patterning
GO:0021766 hippocampus development
GO:0021800 cerebral cortex tangential migration
GO:0030425 dendrite
GO:0032793 positive regulation of CREB transcription factor activity
GO:0038026 reelin-mediated signaling pathway
GO:0043005 neuron projection
GO:0045860 positive regulation of protein kinase activity
GO:0046872 metal ion binding
GO:0048265 response to pain
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050795 regulation of behavior
GO:0050804 modulation of chemical synaptic transmission
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0070325 lipoprotein particle receptor binding
GO:0070326 very-low-density lipoprotein particle receptor binding
GO:0090129 positive regulation of synapse maturation
GO:1900273 positive regulation of long-term synaptic potentiation
GO:2000310 regulation of NMDA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential
GO:2000969 positive regulation of AMPA receptor activity

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR002861 Reeler domainDomainDomain
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR034968 ReelinFamilyFamily
IPR036278 Sialidase superfamilyFamilyHomologous superfamily
IPR041161 Tenascin, EGF-like domainDomainDomain
IPR042307 Reeler domain superfamilyFamilyHomologous superfamily

Diseases

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