Entity Details

Primary name FOXK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01167
EntryNameFOXK2_HUMAN
FullNameForkhead box protein K2
TaxID9606
Evidenceevidence at protein level
Length660
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesFOXK2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001678 cellular glucose homeostasis
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0010507 negative regulation of autophagy
GO:0010906 regulation of glucose metabolic process
GO:0016579 protein deubiquitination
GO:0042594 response to starvation
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061621 canonical glycolysis

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000253 Forkhead-associated (FHA) domainDomainDomain
IPR001766 Fork head domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR018122 Fork head domain conserved site1SiteConserved site
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
FOXK2_HUMANBAP1_HUMANBioGRID, IntAct, MINT19615732 19815555 20805357 24748658 25451922 25609649 27705803 27773593 details
FOXK2_HUMANIRF2_HUMANBioGRID, IntAct, MINT21903422 25609649 28514442 details
FOXK2_HUMANASXL1_HUMANBioGRID, IntAct, MINT25609649 26416890 27705803 32683582 details
FOXK2_HUMANTBL1R_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANTBL1X_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANHCFC1_HUMANBioGRID, MINT24748658 25451922 25609649 details
FOXK2_HUMANSIN3A_HUMANBioGRID, MINT24748658 25609649 27773593 details
FOXK2_HUMANRBBP7_HUMANBioGRID, IntAct26186194 27773593 28514442 details
FOXK2_HUMANESR1_HUMANBioGRID, IntAct25740706 31527615 details
FOXK2_HUMANMTA3_HUMANBioGRID27773593 details
FOXK2_HUMANRCOR1_HUMANBioGRID27773593 details
FOXK2_HUMANRBBP4_HUMANBioGRID27773593 details
FOXK2_HUMANASXL2_HUMANBioGRID, IntAct, MINT24748658 25609649 26416890 27705803 details
FOXK2_HUMANHDAC2_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANNCOR2_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANNCOR1_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANSP130_HUMANBioGRID, MINT25609649 27773593 details
FOXK2_HUMANSAP30_HUMANBioGRID, IntAct, MINT25609649 26496610 27773593 details
FOXK2_HUMANTULP3_HUMANBioGRID, IntAct27173435 28514442 unassigned1312 details
FOXK2_HUMANHDAC1_HUMANBioGRID, IntAct24748658 27773593 28514442 details
FOXK2_HUMANCBX6_HUMANBioGRID21282530 details
FOXK2_HUMANBARD1_HUMANBioGRID25740706 details
FOXK2_HUMANHDAC3_HUMANBioGRID27773593 details
FOXK2_HUMANMTA1_HUMANBioGRID27773593 details
FOXK2_HUMANMTA2_HUMANBioGRID27773593 details
FOXK2_HUMANREST_HUMANBioGRID27773593 details
FOXK2_HUMANSET1B_HUMANBioGRID27773593 details
FOXK2_HUMANIL2_HUMANHPRD9065434 details