Entity Details

Primary name DEF6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01524
EntryNameDEF6_HUMAN
FullNameDefensin-6
TaxID9606
Evidenceevidence at protein level
Length100
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesDEFA6

GO terms

Show/Hide Table
GOName
GO:0002227 innate immune response in mucosa
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0031640 killing of cells of other organism
GO:0042803 protein homodimerization activity
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0050832 defense response to fungus
GO:0051673 membrane disruption in other organism
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0071222 cellular response to lipopolysaccharide

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR002366 Defensin propeptideDomainDomain
IPR006080 Beta/alpha defensinDomainDomain
IPR006081 Alpha-defensinDomainDomain
IPR016327 Alpha-defensin propeptideFamilyFamily

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
DEF6_HUMANUBQL1_HUMANBioGRID, IntAct25416956 31515488 details
DEF6_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details
DEF6_HUMANSGTB_HUMANBioGRID, IntAct32296183 details
DEF6_HUMANA4_HUMANBioGRID21832049 details