Entity Details

Primary name ADCY2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08462
EntryNameADCY2_HUMAN
FullNameAdenylate cyclase type 2
TaxID9606
Evidenceevidence at protein level
Length1091
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesADCY2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006171 cAMP biosynthetic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0008179 adenylate cyclase binding
GO:0016020 membrane
GO:0019933 cAMP-mediated signaling
GO:0030145 manganese ion binding
GO:0030425 dendrite
GO:0034199 activation of protein kinase A activity
GO:0045121 membrane raft
GO:0071377 cellular response to glucagon stimulus
GO:1904322 cellular response to forskolin

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR009398 Adenylate cyclase, conserved domainDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily
IPR030672 Adenylate cyclaseFamilyFamily
IPR032628 Adenylate cyclase, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02587 ColforsinDrugbanksmall molecule
DB06843 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATEDrugbanksmall molecule
DB09121 AurothioglucoseDrugbanksmall molecule