Entity Details

Primary name NOD1
Entity type gene
Source Source Link

Details

PrimaryID10392
RefseqGeneNG_013025
SymbolNOD1
Namenucleotide binding oligomerization domain containing 1
Chromosome7
Location7p14.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-16
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsNOD1_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002221 pattern recognition receptor signaling pathway
GO:0002606 positive regulation of dendritic cell antigen processing and presentation
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007254 JNK cascade
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009595 detection of biotic stimulus
GO:0010942 positive regulation of cell death
GO:0016045 detection of bacterium
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035556 intracellular signal transduction
GO:0038187 pattern recognition receptor activity
GO:0042742 defense response to bacterium
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042834 peptidoglycan binding
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045335 phagocytic vesicle
GO:0046330 positive regulation of JNK cascade
GO:0046658 anchored component of plasma membrane
GO:0050700 CARD domain binding
GO:0050830 defense response to Gram-positive bacterium
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071225 cellular response to muramyl dipeptide
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1904417 positive regulation of xenophagy

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
NOD1RIPK2BioGRID, HPRD, IntAct, MINT, UniProt10224040 10329646 12459189 16517750 17054981 23300079 29997244 details
NOD1NOD1BioGRID, HPRD, UniProt10329646 10880512 18186648 23300079 details
NOD1GABRB1BioGRID, IntAct21988832 details
NOD1SOX8BioGRID, IntAct21988832 details
NOD1XIAPBioGRID, DIP19667203 details
NOD1CRYAA2IntAct32814053 details
NOD1CRYAAIntAct32814053 details
NOD1GFAPIntAct32814053 details
NOD1GLE1IntAct32814053 details
NOD1LMNAIntAct32814053 details
NOD1PAK1IntAct32814053 details
NOD1KLK6IntAct32814053 details
NOD1SPRED1IntAct32814053 details
NOD1HTTIntAct32814053 details
NOD1UBCBioGRID23300079 details
NOD1RNF34BioGRID25012219 details
NOD1ATG16L1BioGRID19898471 23300079 details
NOD1CASP9BioGRID, HPRD, MINT10329646 details
NOD1HSP90AA1BioGRID, IntAct, MINT16083881 17420470 17435760 25036637 details
NOD1HSPA1AMINT16083881 details
NOD1HSPA1BMINT16083881 details
NOD1MAGED1IntAct17353931 details
NOD1FKBP5IntAct25036637 details
NOD1MLF2IntAct25036637 details
NOD1NUDCD3IntAct25036637 details
NOD1PSMD2IntAct25036637 details
NOD1FKBPLIntAct25036637 details
NOD1CDC37IntAct25036637 details
NOD1CACYBPIntAct25036637 details
NOD1PTGES3IntAct25036637 details
NOD1SUGT1BioGRID, DIP, HPIDb17420470 17435760 23935490 details
NOD1OLFM4DIP20534456 details
NOD1HSPB8DIP31273097 details
NOD1NLRC4BioGRID15107016 details
NOD1CARD6BioGRID, HPRD12775719 details
NOD1CASP1BioGRID, HPRD10329646 12459189 details
NOD1CASP2BioGRID, HPRD10329646 details
NOD1CASP4BioGRID, HPRD10329646 details
NOD1CASP8BioGRID, HPRD10329646 details
NOD1CFLARBioGRID10329646 details
NOD1COPS6BioGRID17337451 details
NOD1GPS1BioGRID17337451 details
NOD1TRAF4BioGRID21097508 details
NOD1PSMA7BioGRID23839082 details
NOD1NOD2BioGRID19898471 details
NOD1IRGMBioGRID25891078 details
NOD1NLRP1HPRD11113115 details
NOD1SHMT2BioGRID22658674 details
NOD1MOV10BioGRID22658674 details