Entity Details

Primary name CES1
Entity type gene
Source Source Link

Details

PrimaryID1066
RefseqGeneNG_012057
SymbolCES1
Namecarboxylesterase 1
Chromosome16
Location16q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEST1_HUMAN

GO terms

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GOName
GO:0002003 angiotensin maturation
GO:0004771 sterol esterase activity
GO:0004806 triglyceride lipase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0006695 cholesterol biosynthetic process
GO:0006805 xenobiotic metabolic process
GO:0008203 cholesterol metabolic process
GO:0009636 response to toxic substance
GO:0010875 positive regulation of cholesterol efflux
GO:0010887 negative regulation of cholesterol storage
GO:0016042 lipid catabolic process
GO:0030855 epithelial cell differentiation
GO:0042632 cholesterol homeostasis
GO:0043691 reverse cholesterol transport
GO:0047374 methylumbelliferyl-acetate deacetylase activity
GO:0051791 medium-chain fatty acid metabolic process
GO:0052689 carboxylic ester hydrolase activity
GO:0070857 regulation of bile acid biosynthetic process
GO:0071397 cellular response to cholesterol
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0080030 methyl indole-3-acetate esterase activity
GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport
GO:0090205 positive regulation of cholesterol metabolic process
GO:0120188 regulation of bile acid secretion

Diseases

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Interactions

13 interactions

InteractorPartnerSourcesPublicationsLink
CES1CREB3BioGRID, MINT21516116 details
CES1AHNAK2IntAct32296183 details
CES1EBPIntAct32296183 details
CES1VENTXBioGRID, IntAct32296183 details
CES1PLSCR4BioGRID, IntAct32296183 details
CES1CYSRT1BioGRID, IntAct32296183 details
CES1KPRPBioGRID, IntAct32296183 details
CES1SAR1ABioGRID, IntAct32296183 details
CES1GORABBioGRID, IntAct32296183 details
CES1PDZK1IP1BioGRID, IntAct32296183 details
CES1CES1BioGRID, HPRD12679808 12725862 details
CES1GUSBBioGRID, HPRD10562416 details
CES1BMPR2HPRD15188402 details