Entity Details

Primary name CETP
Entity type gene
Source Source Link

Details

PrimaryID1071
RefseqGeneNG_008952
SymbolCETP
Namecholesteryl ester transfer protein
Chromosome16
Location16q13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-07-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCETP_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005548 phospholipid transporter activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006641 triglyceride metabolic process
GO:0006869 lipid transport
GO:0008203 cholesterol metabolic process
GO:0008289 lipid binding
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010874 regulation of cholesterol efflux
GO:0015485 cholesterol binding
GO:0017129 triglyceride binding
GO:0030301 cholesterol transport
GO:0030522 intracellular receptor signaling pathway
GO:0031210 phosphatidylcholine binding
GO:0031982 vesicle
GO:0032376 positive regulation of cholesterol transport
GO:0034197 triglyceride transport
GO:0034364 high-density lipoprotein particle
GO:0034372 very-low-density lipoprotein particle remodeling
GO:0034374 low-density lipoprotein particle remodeling
GO:0034375 high-density lipoprotein particle remodeling
GO:0042632 cholesterol homeostasis
GO:0043691 reverse cholesterol transport
GO:0046470 phosphatidylcholine metabolic process
GO:0055088 lipid homeostasis
GO:0055091 phospholipid homeostasis
GO:0070062 extracellular exosome
GO:0070328 triglyceride homeostasis
GO:0120020 cholesterol transfer activity
GO:2001140 positive regulation of phospholipid transport

Diseases

Show/Hide Table
Disease IDSourceNameDescription
143470 OMIMHyperalphalipoproteinemia 1 (HALP1)A condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. The disease is caused by variants affecting the gene represented in this entry.

Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
CETPARPC3HPRD, IntAct16169070 details
CETPEWSR1BioGRID, HPRD, IntAct16189514 details
CETPPRKACGBioGRID, IntAct21988832 details
CETPTP53BioGRID27229929 details
CETPLPLHPRD9374130 details
CETPAPOA1HPRD9305883 details
CETPCETPHPRD3818596 details