Entity Details

Primary name MTHFD2
Entity type gene
Source Source Link

Details

PrimaryID10797
RefseqGeneNG_029162
SymbolMTHFD2
Namemethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Chromosome2
Location2p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMTDC_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004477 methenyltetrahydrofolate cyclohydrolase activity
GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0035999 tetrahydrofolate interconversion
GO:0042301 phosphate ion binding
GO:0046653 tetrahydrofolate metabolic process
GO:0046655 folic acid metabolic process

Diseases

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Interactions

74 interactions

InteractorPartnerSourcesPublicationsLink
MTHFD2NAGKBioGRID, IntAct, MINT21516116 25416956 32296183 details
MTHFD2DAPK1BioGRID, IntAct29513927 details
MTHFD2PTENBioGRID26561776 details
MTHFD2LMNABioGRID24623722 details
MTHFD2MCCIntAct17353931 details
MTHFD2MICOS10BioGRID22114354 details
MTHFD2PSMD13BioGRID, IntAct17353931 details
MTHFD2PARP3BioGRID, IntAct17353931 details
MTHFD2CUL3BioGRID, IntAct21145461 details
MTHFD2LRRK2IntAct24725412 31046837 details
MTHFD2HSCBBioGRID, IntAct28380382 details
MTHFD2ACAA1BioGRID, IntAct26186194 28514442 details
MTHFD2SRP9BioGRID, IntAct28514442 details
MTHFD2UBP1BioGRID, IntAct28514442 details
MTHFD2MTHFD2LBioGRID, IntAct28514442 details
MTHFD2TFCP2BioGRID, IntAct28514442 details
MTHFD2ACADLBioGRID, IntAct28514442 details
MTHFD2HRASBioGRID, IntAct28514442 details
MTHFD2HSPD1BioGRID, IntAct29568061 details
MTHFD2MGST3IntAct29568061 details
MTHFD2PDK1BioGRID, IntAct29568061 details
MTHFD2TRMT61BBioGRID, IntAct29568061 details
MTHFD2DLDBioGRID, IntAct29128334 details
MTHFD2MAB21L2BioGRID, IntAct30833792 details
MTHFD2DHX40BioGRID22939629 details
MTHFD2GCC1BioGRID22939629 details
MTHFD2DHX29BioGRID22939629 details
MTHFD2HUWE1BioGRID25147182 details
MTHFD2CLIC1BioGRID26344197 details
MTHFD2NFATC1BioGRID27637333 details
MTHFD2NFATC2BioGRID27637333 details
MTHFD2DUSP13BioGRID27432908 details
MTHFD2ATXN3BioGRID29111377 details
MTHFD2SNAI1BioGRID29331416 details
MTHFD2MRM1BioGRID29568061 details
MTHFD2PHBBioGRID27025967 details
MTHFD2UBQLN2BioGRID30442662 details
MTHFD2ABHD11BioGRID31536960 details
MTHFD2PEBP1BioGRID31536960 details
MTHFD2LAMTOR2BioGRID31536960 details
MTHFD2AK4BioGRID31536960 details
MTHFD2HCCSBioGRID31536960 details
MTHFD2TXNDC12BioGRID31536960 details
MTHFD2MSRB2BioGRID31536960 details
MTHFD2LYPLA1BioGRID31536960 details
MTHFD2AK2BioGRID31536960 details
MTHFD2PRDX5BioGRID31536960 details
MTHFD2PLEKHA4BioGRID31091453 details
MTHFD2ANLNBioGRID31586073 details
MTHFD2KIF14BioGRID31586073 details
MTHFD2BRD8BioGRID31753913 details
MTHFD2AUHBioGRID32877691 details
MTHFD2C1QBPBioGRID32877691 details
MTHFD2GATD3BioGRID32877691 details
MTHFD2MTRES1BioGRID32877691 details
MTHFD2MCUR1BioGRID32877691 details
MTHFD2MDH2BioGRID32877691 details
MTHFD2METTL17BioGRID32877691 details
MTHFD2MTG2BioGRID32877691 details
MTHFD2MTIF2BioGRID32877691 details
MTHFD2PMPCBBioGRID32877691 details
MTHFD2SSBP1BioGRID32877691 details
MTHFD2TMEM70BioGRID32877691 details
MTHFD2TSFMBioGRID32877691 details
MTHFD2TUFMBioGRID32877691 details
MTHFD2CLPPBioGRID31056398 details
MTHFD2NMRAL1BioGRID31796584 details
MTHFD2PRKNBioGRID32929329 details
MTHFD2UFL1BioGRID32807901 details
MTHFD2AARS2BioGRID34079125 details
MTHFD2COX8ABioGRID34079125 details
MTHFD2CSBioGRID34079125 details
MTHFD2PDHA1BioGRID34079125 details
MTHFD2ELAVL1BioGRID19322201 details