Entity Details

Primary name SLC26A8
Entity type gene
Source Source Link

Details

PrimaryID116369
RefseqGeneNG_033897
SymbolSLC26A8
Namesolute carrier family 26 member 8
Chromosome6
Location6p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-10-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsS26A8_HUMAN

GO terms

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GOName
GO:0005254 chloride channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006820 anion transport
GO:0006821 chloride transport
GO:0007275 multicellular organism development
GO:0008271 secondary active sulfate transmembrane transporter activity
GO:0008272 sulfate transport
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015116 sulfate transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
GO:0019531 oxalate transmembrane transporter activity
GO:0019532 oxalate transport
GO:0030317 flagellated sperm motility
GO:0048240 sperm capacitation
GO:0051321 meiotic cell cycle

Diseases

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Disease IDSourceNameDescription
606766 OMIMSpermatogenic failure 3 (SPGF3)A disorder characterized by primary infertility, sperm morphologic abnormalities, and moderate to severe asthenozoospermia, condition in which the percentage of progressively motile sperm is abnormally low. The disease is caused by variants affecting the gene represented in this entry.

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SLC26A8RACGAP1BioGRID, HPRD, IntAct11278976 details
SLC26A8CFTRUniProt22121115 details
SLC26A8NXF1BioGRID7707528 details