Entity Details

Primary name ALKB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13686
EntryNameALKB1_HUMAN
FullNameNucleic acid dioxygenase ALKBH1
TaxID9606
Evidenceevidence at protein level
Length389
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesALKBH1

GO terms

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GOName
GO:0000049 tRNA binding
GO:0000791 euchromatin
GO:0001701 in utero embryonic development
GO:0001764 neuron migration
GO:0001890 placenta development
GO:0002101 tRNA wobble cytosine modification
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0006281 DNA repair
GO:0006307 DNA dealkylation involved in DNA repair
GO:0006446 regulation of translational initiation
GO:0006448 regulation of translational elongation
GO:0008198 ferrous iron binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031175 neuron projection development
GO:0035513 oxidative RNA demethylation
GO:0035515 oxidative RNA demethylase activity
GO:0035516 oxidative DNA demethylase activity
GO:0035552 oxidative single-stranded DNA demethylation
GO:0042056 chemoattractant activity
GO:0042245 RNA repair
GO:0043524 negative regulation of neuron apoptotic process
GO:0048589 developmental growth
GO:0070129 regulation of mitochondrial translation
GO:0070579 methylcytosine dioxygenase activity
GO:0070989 oxidative demethylation
GO:0080111 DNA demethylation
GO:0103053 1-ethyladenine demethylase activity
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:1990983 tRNA demethylation
GO:1990984 tRNA demethylase activity

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR004574 Alkylated DNA repair protein AlkBFamilyFamily
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-likeDomainDomain
IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ALKB1_HUMANDNJB6_HUMANBioGRID18163532 details