Entity Details

Primary name ERCC1
Entity type gene
Source Source Link

Details

PrimaryID2067
RefseqGeneNG_015839
SymbolERCC1
NameERCC excision repair 1, endonuclease non-catalytic subunit
Chromosome19
Location19q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-04-16
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsERCC1_HUMAN

GO terms

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GOName
GO:0000109 nucleotide-excision repair complex
GO:0000110 nucleotide-excision repair factor 1 complex
GO:0000710 meiotic mismatch repair
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair
GO:0000781 chromosome, telomeric region
GO:0001094 TFIID-class transcription factor complex binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0004519 endonuclease activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006312 mitotic recombination
GO:0006949 syncytium formation
GO:0006979 response to oxidative stress
GO:0007283 spermatogenesis
GO:0007584 response to nutrient
GO:0008022 protein C-terminus binding
GO:0008283 cell population proliferation
GO:0008584 male gonad development
GO:0009650 UV protection
GO:0009744 response to sucrose
GO:0010165 response to X-ray
GO:0010259 multicellular organism aging
GO:0019904 protein domain specific binding
GO:0032205 negative regulation of telomere maintenance
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035166 post-embryonic hemopoiesis
GO:0035264 multicellular organism growth
GO:0035902 response to immobilization stress
GO:0036297 interstrand cross-link repair
GO:0045190 isotype switching
GO:0046686 response to cadmium ion
GO:0048477 oogenesis
GO:0048568 embryonic organ development
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0061819 telomeric DNA-containing double minutes formation
GO:0070522 ERCC4-ERCC1 complex
GO:0070911 global genome nucleotide-excision repair
GO:0070914 UV-damage excision repair
GO:0090399 replicative senescence
GO:0090656 t-circle formation
GO:1904431 positive regulation of t-circle formation
GO:1905765 negative regulation of protection from non-homologous end joining at telomere
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
ERCC1UBL7BioGRID, HPRD, IntAct16189514 25416956 25910212 details
ERCC1XPABioGRID, DIP, HPRD, IntAct11058119 16491090 17948053 18597777 19056823 24036546 25416956 26186194 28514442 32296183 7598728 8197174 9013642 9653453 details
ERCC1SLX4BioGRID, IntAct19595721 19596235 19596236 21240275 22902628 23033263 23093618 23623386 25538220 26186194 28514442 31495888 32398829 details
ERCC1SLX1ABioGRID, IntAct19595721 19596235 28514442 details
ERCC1MKRN3BioGRID, IntAct25416956 details
ERCC1USHBP1BioGRID, IntAct25416956 details
ERCC1TRMT2BBioGRID, IntAct25416956 details
ERCC1VPS37BBioGRID, IntAct25416956 31515488 details
ERCC1ERCC4BioGRID, DIP, HPRD, IntAct10413517 11160918 14706347 14734547 15932882 16076955 16338413 17289582 17912758 19940136 21466675 21875596 22353549 22939629 23580445 24036546 24780295 25538220 25956741 26085086 26186194 26344197 26453996 28514442 31495888 8197175 9013642 9722633 details
ERCC1GAS8BioGRID, IntAct32296183 details
ERCC1CHRM5BioGRID, MINT28298427 details
ERCC1FANCGBioGRID20518486 details
ERCC1UHRF1BioGRID25818288 details
ERCC1APPBioGRID21244100 details
ERCC1USP45BioGRID25538220 30258100 details
ERCC1RPA1BioGRID24036546 details
ERCC1RPA2BioGRID24036546 details
ERCC1RPA3BioGRID24036546 details
ERCC1KIF11BioGRID22353549 details
ERCC1RAD52BioGRID14734547 details
ERCC1EGFRBioGRID, IntAct24780295 details
ERCC1MUS81BioGRID, IntAct25538220 28514442 details
ERCC1SLX4IPBioGRID, IntAct26186194 28514442 31495888 details
ERCC1CASS4IntAct31413325 details
ERCC1GTF2H1BioGRID11259578 details
ERCC1TAF6BioGRID22323595 details
ERCC1TAF7BioGRID22323595 details
ERCC1TAF10BioGRID22323595 details
ERCC1TAF12BioGRID22323595 details
ERCC1TBPBioGRID22323595 details
ERCC1POLR2ABioGRID16916636 details
ERCC1MSH2BioGRID14706347 details
ERCC1SPTA1BioGRID16889989 details
ERCC1ERCC1BioGRID28903417 details
ERCC1MAD2L1BioGRID18597777 details
ERCC1DCAF7BioGRID31493872 details
ERCC1SLX1BBioGRID, IntAct19596235 28514442 details
ERCC1CDC5LBioGRID, MINT20467437 details
ERCC1DCAF1IntAct24412650 details
ERCC1ZFC3H1BioGRID, IntAct28514442 details
ERCC1MAGIXBioGRID, IntAct26186194 28514442 details
ERCC1RNF8DIP26503038 details
ERCC1TP53BP1BioGRID, UniProt29656893 details
ERCC1BRCA1BioGRID, UniProt29656893 details
ERCC1MDC1BioGRID, UniProt29656893 details
ERCC1ACAT1BioGRID26344197 details
ERCC1C15orf40BioGRID26344197 details
ERCC1TOPBP1BioGRID26344197 details
ERCC1TWF2BioGRID26344197 details
ERCC1SPDL1BioGRID30258100 details
ERCC1H2BC8BioGRID34079125 details
ERCC1SNAI1IntAct25314079 details
ERCC1CREBBPIntAct25314079 details