Entity Details

Primary name TFDP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14188
EntryNameTFDP2_HUMAN
FullNameTranscription factor Dp-2
TaxID9606
Evidenceevidence at protein level
Length446
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTFDP2

GO terms

Show/Hide Table
GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000785 chromatin
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0019904 protein domain specific binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070317 negative regulation of G0 to G1 transition
GO:0072686 mitotic spindle
GO:0090575 RNA polymerase II transcription regulator complex
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR014889 Transcription factor DP, C-terminalDomainDomain
IPR015648 Transcription factor DPFamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily
IPR038168 Transcription factor DP, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table