Entity Details

Primary name ICOSLG
Entity type gene
Source Source Link

Details

PrimaryID23308
RefseqGene
SymbolICOSLG
Nameinducible T cell costimulator ligand
Chromosome21
Location21q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsICOSL_HUMAN

GO terms

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GOName
GO:0001817 regulation of cytokine production
GO:0002250 adaptive immune response
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0006952 defense response
GO:0006972 hyperosmotic response
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0031295 T cell costimulation
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042104 positive regulation of activated T cell proliferation
GO:0042110 T cell activation
GO:0042113 B cell activation
GO:0042802 identical protein binding
GO:0050852 T cell receptor signaling pathway
GO:0070062 extracellular exosome

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
ICOSLGICOSBioGRID, HPRD, IntAct10657606 11023515 11956294 16951355 28514442 details
ICOSLGICOSLGIntAct16951355 details
ICOSLGPREBBioGRID, IntAct28514442 details
ICOSLGZDHHC6BioGRID, IntAct28514442 details
ICOSLGPTPRDBioGRID, IntAct28514442 details
ICOSLGLGALS1BioGRID, IntAct28514442 details
ICOSLGC2CD2LBioGRID, IntAct28514442 details
ICOSLGUPK3BL1BioGRID, IntAct28514442 details
ICOSLGVIRMABioGRID29507755 details