Entity Details

Primary name DHX8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14562
EntryNameDHX8_HUMAN
FullNameATP-dependent RNA helicase DHX8
TaxID9606
Evidenceevidence at protein level
Length1220
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesDHX8

GO terms

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GOName
GO:0000390 spliceosomal complex disassembly
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0016604 nuclear body
GO:0042802 identical protein binding
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR003029 S1 domainDomainDomain
IPR007502 Helicase-associated domainDomainDomain
IPR011709 Domain of unknown function DUF1605DomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR022967 RNA-binding domain, S1DomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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