Entity Details

Primary name GCHFR
Entity type gene
Source Source Link

Details

PrimaryID2644
RefseqGene
SymbolGCHFR
NameGTP cyclohydrolase I feedback regulator
Chromosome15
Location15q15.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGFRP_HUMAN

GO terms

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GOName
GO:0004857 enzyme inhibitor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006809 nitric oxide biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0016597 amino acid binding
GO:0030425 dendrite
GO:0030742 GTP-dependent protein binding
GO:0031965 nuclear membrane
GO:0032991 protein-containing complex
GO:0042133 neurotransmitter metabolic process
GO:0042470 melanosome
GO:0043105 negative regulation of GTP cyclohydrolase I activity
GO:0044549 GTP cyclohydrolase binding
GO:0044877 protein-containing complex binding
GO:0046146 tetrahydrobiopterin metabolic process
GO:0065003 protein-containing complex assembly

Diseases

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Interactions

16 interactions

InteractorPartnerSourcesPublicationsLink
GCHFRGCH1BioGRID, HPRD, IntAct16696853 8702680 details
GCHFRGCHFRHPRD9092499 details
GCHFRSPINK2BioGRID, IntAct28514442 details
GCHFRPUSL1BioGRID, IntAct28514442 details
GCHFRHBS1LBioGRID, IntAct28514442 details
GCHFRCAMKK2BioGRID, IntAct28514442 details
GCHFRIRF2BP2BioGRID, IntAct28514442 details
GCHFRDOCK11BioGRID, IntAct28514442 details
GCHFRCBFBBioGRID, IntAct28514442 details
GCHFREIF4G1BioGRID, IntAct28514442 details
GCHFRNEBLBioGRID, IntAct28514442 details
GCHFROBSL1BioGRID, IntAct28514442 details
GCHFRFXYD1BioGRID, IntAct28514442 details
GCHFRMYCBioGRID20848231 details
GCHFRMOV10BioGRID22658674 details
GCHFRDDX58BioGRID32513696 details